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The Church of the Holy Cross at Sambuci was built in 1662 and can be found on Via Girolamo Theodoli. The plaster covered brick facade features the Astalli crest, tympanum and pilasters. The portal is in travertine marble while the bell tower is characterised by arched windows.
The interior of the church, decorated with contemporary fake marble, contains a crucifix and paintings of St. Joseph and the Madonna of Mount Carmel above the two small altars.